I rolled my eyes when I saw a mention of this movie a few days ago. I even joked about Samuel L. Jackson's decision to make this movie. But looks like many other people have a different view:

[Samuel L.] Jackson stars as an FBI agent who has to fight a planeload of snakes unleashed by an assassin bent on killing a witness in protective custody. Sight unseen, the movie has grown from something of a joke into a phenomenon slithering untamed throughout the Internet... the movie already is the talk of a certain segment of the Net... It all started with the provocative and buzzworthy, if also reductive, title... there were skeptics who viewed "Snakes on a Plane" as nothing but a simple programmer with a "stupid title"... "Who wants to be in a movie called "Snakes on a Plane'?" asked one talent agent at the time... But once production began, a funny thing happened. Movie fans began noticing... They seized upon the title and created fan sites, blogs, T-shirts, poems, fiction and songs. The title itself, sometimes abbreviated as "SoaP," has emerged as Internet-speak for fatalistic sentiments that range from c'est la vie to "s--- happens."... "That's the only reason I took the job: I read the title," Jackson [said]. He added, "You either want to see that, or you don't."